* p < 0,0001 < PL ; + p < 0,01 vs SSZ : ++ p = 0,0149 vs SSZ

> Kalden JR, Scott DL, Smolen JS et al. Improved functional ability in patients with rheumatoid arthritis--longterm treatment with leflunomide versus sulfasalazine. European Leflunomide Study Group. J Rheumatol. 2001 Sep;28(9):1983-91.